Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | CCR3 | P51677 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425957 | 0.88 | SIGMAR1 (0.90) | SIGMAR1POLBCCR3KMT2AHTT | |
| SCHEMBL1711070 | 0.83 | SIGMAR1 (1.00) | SIGMAR1POLBCCR3KMT2AHTT | |
| SCHEMBL9154819 | 0.82 | SIGMAR1 (0.57) | SIGMAR1POLBKMT2AHTTMEN1 | |
| SCHEMBL9154279 | 0.82 | SIGMAR1 (0.57) | SIGMAR1POLBKMT2AHTTMEN1 | |
| SCHEMBL9249340 | 0.80 | POLB (0.47) | SIGMAR1POLBKMT2AKDM1AMEN1 | |
| SCHEMBL8092982 | 0.78 | SIGMAR1 (0.85) | SIGMAR1CCR3KMT2AMEN1TP53 | |
| Hydrochloric Acid SCHEMBL9716493 | 0.78 | SIGMAR1 (0.42) | SIGMAR1POLBCCR3 | |
| SCHEMBL7394691 | 0.77 | SIGMAR1 (0.68) | SIGMAR1POLBCCR3KMT2AMEN1 | |
| SCHEMBL7397638 | 0.77 | SIGMAR1 (0.68) | SIGMAR1POLBCCR3KMT2AMEN1 | |
| SCHEMBL78043 | 0.77 | SIGMAR1 (0.79) | SIGMAR1POLBCCR3KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429370-B1 | Thiophene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-01-04 | — | — | EP | claimed |