Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15384643 | 0.83 | NR3C1 (0.49) | SLC6A2SLC6A4SLC6A3LMNAPKM | |
| SCHEMBL13338024 | 0.81 | CYP19A1 (0.44) | SLC6A2SLC6A4SLC6A3LMNASMN1; SMN2 | |
| SCHEMBL27493256 | 0.78 | SMN1; SMN2 (0.43) | MAT2ASMN1; SMN2ALDH1A1KDM4ETSHR | |
| SCHEMBL6823718 | 0.77 | NTRK1 (0.40) | SLC6A4LMNAPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL11156758 | 0.77 | MEN1 (0.49) | MAT2ASMN1; SMN2ALDH1A1KDM4ETSHR | |
| SCHEMBL27564387 | 0.76 | MEN1 (0.45) | MAT2ALMNAALDH1A1KDM4EGAA | |
| SCHEMBL3423087 | 0.75 | CRHBP (0.57) | LMNAPKMALDH1A1MAPT | |
| Formic Acid SCHEMBL6820433 | 0.73 | ACHE (0.47) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3424749 | 0.72 | GAA (0.44) | LMNASMN1; SMN2ALDH1A1KDM4ETSHR | |
| SCHEMBL8263076 | 0.72 | NR1H2 (0.54) | MAT2ASMN1; SMN2ALDH1A1NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479671-B1 | Pyrimidinone compounds | SMITHKLINE BEECHAM PLC (GB) | 2009-05-27 | — | — | EP | disclosed |