Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410966 | 0.84 | HSD17B10 (0.44) | ALDH1A1MAPTGAA | |
| SCHEMBL442625 | 0.81 | POLB (0.46) | ALDH1A1MAPTGAANPC1RAB9A | |
| SCHEMBL5324207 | 0.77 | HPGD (0.43) | ALDH1A1MAPTCA12GAALMNA | |
| SCHEMBL15570209 | 0.76 | CSF1R (0.42) | ALDH1A1GAALMNANPC1RAB9A | |
| SCHEMBL7996778 | 0.72 | ALDH1A1 (0.52) | ALDH1A1GAALMNACNR2TDP1 | |
| SCHEMBL11256419 | 0.72 | ALDH1A1 (0.49) | ALDH1A1MAPTGAALMNANPC1 | |
| SCHEMBL1819856 | 0.72 | HPGD (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29388433 | 0.72 | ALDH1A1 (0.50) | ALDH1A1GAANPC1RAB9ATDP1 | |
| SCHEMBL29564582 | 0.71 | CA12 (0.48) | ALDH1A1MAPTCA12CA1MMP8 | |
| SCHEMBL29157097 | 0.71 | CTSA (0.43) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065208-A1 | CANCER TREATMENT | Electronic Patent Assignments System (EPAS) | 2012-03-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065208-A1 | CANCER TREATMENT | BRCA1, VHL, MGMT | ALDH1A1 618/4885MAPT 2160/4885CA12 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.