Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442624 | 0.81 | ALDH1A1 (0.52) | NPC1RAB9AALDH1A1GAATDP1 | |
| SCHEMBL11256419 | 0.81 | ALDH1A1 (0.49) | POLBNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL5968639 | 0.77 | POLB (0.50) | POLBNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL410966 | 0.77 | HSD17B10 (0.44) | ALDH1A1GAAMAPTMAPK1HSD17B10 | |
| SCHEMBL11206858 | 0.76 | CLCN2 (0.42) | POLBNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL7996778 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HPGDGAATDP1MEN1 | |
| SCHEMBL29388433 | 0.74 | ALDH1A1 (0.50) | POLBNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL2483409 | 0.72 | RAB9A (0.48) | POLBNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL15570209 | 0.72 | CSF1R (0.42) | POLBNPC1RAB9AALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL1695958 | 0.71 | RAB9A (0.47) | POLBNPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065208-A1 | CANCER TREATMENT | Electronic Patent Assignments System (EPAS) | 2012-03-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065208-A1 | CANCER TREATMENT | BRCA1, VHL, MGMT | POLB 1513/4885NPC1 174/4885RAB9A 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.