Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361735 | 0.85 | NPC1 (0.46) | HPGDALDH1A1HSD17B10LMNAATM | |
| SCHEMBL1819856 | 0.83 | HPGD (0.50) | HPGDACP3ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3724579 | 0.80 | ALDH1A1 (0.44) | HPGDACP3ALDH1A1L3MBTL1ESR1 | |
| SCHEMBL16371412 | 0.79 | ALDH1A1 (0.43) | HPGDACP3ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL9298098 | 0.79 | VDR (0.43) | HPGDACP3TDP1ALDH1A1LMNA | |
| SCHEMBL2482538 | 0.79 | GAA (0.45) | TDP1ALDH1A1LMNAL3MBTL1CA12 | |
| SCHEMBL9298090 | 0.79 | VDR (0.43) | HPGDACP3TDP1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2485774 | 0.77 | GAA (0.44) | TDP1ALDH1A1LMNAL3MBTL1CA12 | |
| SCHEMBL442624 | 0.77 | ALDH1A1 (0.52) | TDP1ALDH1A1LMNACA12MAPT | |
| SCHEMBL3123356 | 0.77 | TDP1 (0.36) | HPGDACP3TDP1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399570-A | Aspartic acid derivatives, and their use for inhibiting platelete aggregation | CASSELLA AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | claimed |
| WO-2007008942-A2 | PHENYLAMINO-ACETIC ACID [1-(PYRIDIN-4-YL)-METHYLIDENE]-HYDRAZIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF G PROTEIN-COUPLED RECEPTOR KINASES FOR THE TREATMENT OF EYE DISEASES | AERIE PHARMACEUTICALS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |