SCHEMBL4426504

SCHEMBL4426504

CC(C)C(NP(=O)(Cl)Cl)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 1/20 0.32
ALDH1A1 P00352 1/20 0.32
BCHE P06276 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10586052 0.78 LAP3 (0.35) LAP3
SCHEMBL4345976 0.75
SCHEMBL12208290 0.67
SCHEMBL10873350 0.67
SCHEMBL15828291 0.63 ALDH1A1 (0.31) ALDH1A1BCHEHIF1A
SCHEMBL15828301 0.63 ALDH1A1 (0.31) ALDH1A1BCHEHIF1A
SCHEMBL11815965 0.63 ALDH1A1 (0.48) ALDH1A1BCHEHIF1A
SCHEMBL11270722 0.59
SCHEMBL1919886 0.59 ALDH1A1 (0.43) ALDH1A1BCHEHIF1A
SCHEMBL2020126 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021061154-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2021-04-01 WO disclosed
US-9637515-B2 Guggulphospholipid methods and compositions JINA PHARMACEUTICALS, INC. (US) 2017-05-02 US disclosed
EP-2088865-A2 GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS Jina Pharmaceuticals Inc. (US) 2009-08-19 EP disclosed
WO-2008058156-A9 GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS JINA PHARMACEUTICALS INC (US) 2008-12-04 WO disclosed
WO-2008058156-A2 GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS JINA PHARMACEUTICALS INC. (US) 2008-05-15 WO disclosed
US-5962498-A Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity PROCYON PHARMACEUTICALS, INC. (US) 1999-10-05 US disclosed
EP-0553107-A1 PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY PROCYON PHARMACEUTICALS, INC. (US) 1993-08-04 EP disclosed
EP-0320942-A2 Novel polysaccharides novel macromolecular conjugates of the polysaccharides AMERICAN CYANAMID COMPANY (US) 1989-06-21 EP disclosed
EP-0313219-A2 Non-nucleotide linking reagents for nucleotide probes GEN-PROBE INCORPORATED (US) 1989-04-26 EP disclosed
WO-1989002439-A1 NON-NUCLEOTIDE LINKING REAGENTS FOR NUCLEOTIDE PROBES ML TECHNOLOGY VENTURES, L.P. (US) 1989-03-23 WO disclosed