Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29492790 | 0.98 | ALDH1A1 (0.43) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL24869826 | 0.86 | CYP3A4 (0.43) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL29502984 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL18702751 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL16756041 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL2142119 | 0.81 | TDP1 (0.55) | ALDH1A1TDP1TSHRLMNAMAPT | |
| SCHEMBL5951484 | 0.81 | NR4A1 (0.56) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL29373010 | 0.81 | NR4A1 (0.56) | ALDH1A1TDP1CYP3A4TSHRLMNA | |
| SCHEMBL5733721 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1TDP1TSHRLMNAMAPT | |
| SCHEMBL1981296 | 0.80 | ALOX15 (0.42) | ALDH1A1CYP3A4TSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362369-B1 | — | — | None | — | — | US | disclosed |
| EP-4694980-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS INHIBITORS OF NLRP3 | Takeda Pharmaceutical Company Limited (JP) | 2026-02-18 | — | — | EP | disclosed |
| CN-119192200-A | Bicyclic heterocyclic compounds, preparation method and medical application thereof | 华润医药研究院（深圳）有限公司 | 2024-12-27 | — | — | CN | disclosed |
| WO-2024211969-A1 | PPARG MODULATORS | Setonix Pharmaceuticals Pty Ltd (AU) | 2024-10-17 | — | — | WO | disclosed |
| WO-2024214046-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS INHIBITORS OF NLRP3 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-10-17 | — | — | WO | disclosed |
| US-20240150277-A1 | Covalent PPARG inverse-agonists | BAYER AKTIENGESELLSCHAFT (DE) | 2024-05-09 | — | — | US | disclosed |
| US-20230365559-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | AUCKLAND UNISERVICES LIMITED (NZ) | 2023-11-16 | — | — | US | disclosed |
| US-20230227483-A1 | PYRIMIDINE COMPOUNDS FOR USE AS MAP4K1 INHIBITORS | GLENMARK SPECIALITY S.A. (CH) | 2023-07-20 | — | — | US | disclosed |
| US-20230103791-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-04-06 | — | — | US | disclosed |
| US-20210277003-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-09 | — | — | US | disclosed |
| US-6559341-B2 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 2003-05-06 | — | — | US | disclosed |
| US-20030055287-A1 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | AIR MOTION TECHNOLOGIES, LLC | 2003-03-20 | — | — | US | disclosed |
| US-6362369-B2 | CONTROLLING INSECTS IN CROPS | NIHON NOHYAKU CO., LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-20010041814-A1 | PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-0919542-A2 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 1999-06-02 | — | — | EP | disclosed |
| EP-0411200-B1 | Oxazoline compounds and herbicides containing the same | SDS BIOTECH CORP (JP) | 1994-04-13 | — | — | EP | disclosed |
| EP-0411200-A1 | Oxazoline compounds and herbicides containing the same | SDS BIOTECH K.K. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4973351-A | 4-PHENYLAMINO-3-OXAZOLIN-5-ONE | SDS BIOTECH KABUSHIKI KAISHA (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4623378-A | HYBRIIZATION OF PLANTS | CIBA-GEIGY CORPORATION (US) | 1986-11-18 | — | — | US | disclosed |
| EP-0136974-A2 | Pyridazinylcarboxylic acid derivatives having a gametocide activity | CIBA-GEIGY AG (CH) | 1985-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150277-A1 | Covalent PPARG inverse-agonists | PPARG, PPARD, PPARA | ALDH1A1 1224/4885TDP1 3700/4885CYP3A4 672/4885 |
| US-20010041814-A1 | PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES | DDT, AFF1, BCL2L2 | ALDH1A1 252/4885TDP1 888/4885CYP3A4 2718/4885 |
| US-20230103791-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | SCN8A, SCN1A, SCN1B | ALDH1A1 3102/4885TDP1 829/4885CYP3A4 2550/4885 |
| US-20030055287-A1 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | DDT, BCL2A1, BCL2L2 | ALDH1A1 269/4885TDP1 846/4885CYP3A4 2858/4885 |
| US-20210277003-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | ALDH1A1 3839/4885TDP1 83/4885CYP3A4 4278/4885 |
| US-20230365559-A1 | NOVEL AMINOPYRIDINES AND THEIR USE IN TREATING CANCER | DCK, DTYMK, TYMP | ALDH1A1 1620/4885TDP1 78/4885CYP3A4 1178/4885 |
| US-20230227483-A1 | PYRIMIDINE COMPOUNDS FOR USE AS MAP4K1 INHIBITORS | MAP4K1, MAP3K4, MAP4K2 | ALDH1A1 2196/4885TDP1 297/4885CYP3A4 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.