Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.76 |
| ▸ | CA4 | P22748 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | DAO | P14920 | 1/20 | 0.70 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.70 |
| ▸ | CES2 | O00748 | 3/20 | 0.58 |
| ▸ | CES1 | P23141 | 3/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL28139587 | 0.95 | CA2 (0.70) | CA2CA4TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL455262 | 0.95 | CA2 (0.85) | CA2CA4TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL2591456 | 0.95 | CA2 (0.85) | CA2CA4TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL11791472 | 0.95 | CA2 (0.85) | CA2CA4TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL17507463 | 0.95 | CA2 (0.76) | CA2CA4TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL27469815 | 0.93 | CA2 (0.81) | CA2CA4TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL27970515 | 0.93 | CA2 (0.73) | CA2CA4TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL28255902 | 0.93 | CA2 (0.81) | CA2CA4TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL395155 | 0.93 | CA2 (0.73) | CA2CA4TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL28092207 | 0.93 | CA2 (0.73) | CA2CA4TSHRDAONAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631040-B | Compositions and methods for controlling plant pests and improving plant health | 农业生物群落股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-113973845-B | Compositions and methods for controlling plant disease | 农业生物群落股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-113163771-B | Compositions and methods for controlling plant pests and improving plant health | 农业生物群落股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-114173562-A | Compositions and methods for improving plant health and controlling plant disease | 农业生物群落股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113631040-A | Compositions and methods for controlling plant pests and improving plant health | 农业生物群落股份有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-108135178-B | Compositions and methods for controlling plant disease | 农业生物群落股份有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-113163771-A | Compositions and methods for controlling plant pests and improving plant health | 农业生物群落股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20090324656-A1 | COSMETIC PREPARATIONS WITH AN ADDITIVE FROM THE BAOBAB TREE | ENGELS PETER | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324656-A1 | COSMETIC PREPARATIONS WITH AN ADDITIVE FROM THE BAOBAB TREE | CUTA, BROX, MANBA | CA2 4291/4885CA4 3068/4885TSHR 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.