Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44304 | 0.87 | KCNH2 (0.43) | MEN1KMT2AALDH1A1LMNATP53 | |
| SCHEMBL44623 | 0.86 | FFAR1 (0.42) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL44472 | 0.85 | HTT (0.40) | KMT2ATSHRTP53 | |
| SCHEMBL45433 | 0.85 | GLA (0.37) | KMT2AALDH1A1 | |
| SCHEMBL44282 | 0.84 | PPARA (0.41) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL44594 | 0.83 | HTR1A (0.39) | MEN1KMT2AALDH1A1LMNATP53 | |
| SCHEMBL44314 | 0.82 | HDAC4 (0.42) | ALDH1A1LMNAHPGDTP53 | |
| SCHEMBL44365 | 0.82 | NOTUM (0.50) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL44040 | 0.81 | SMN1; SMN2 (0.39) | KMT2AALDH1A1LMNATSHRATM | |
| Alcohol SCHEMBL43983 | 0.81 | NOTUM (0.38) | MEN1KMT2AALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |