Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44623 | 0.91 | FFAR1 (0.42) | KMT2ANPC1RAB9AALDH1A1FFAR1 | |
| SCHEMBL44472 | 0.88 | HTT (0.40) | GLAKMT2AMAPT | |
| SCHEMBL44365 | 0.86 | NOTUM (0.50) | KMT2APTPN1NPC1RAB9AALDH1A1 | |
| SCHEMBL44277 | 0.85 | MEN1 (0.42) | KMT2AALDH1A1 | |
| SCHEMBL44304 | 0.85 | KCNH2 (0.43) | KMT2AALDH1A1MAPTTHRB | |
| Hydrochloric Acid SCHEMBL45038 | 0.85 | NOTUM (0.41) | KMT2APTPN1NPC1RAB9AALDH1A1 | |
| SCHEMBL44354 | 0.84 | HPGD (0.45) | KMT2AALDH1A1POLB | |
| SCHEMBL44170 | 0.84 | GAA (0.41) | NR4A2NPC1RAB9AMAPTTHRB | |
| SCHEMBL44711 | 0.84 | MAPT (0.43) | KMT2ANPC1RAB9AMAPT | |
| SCHEMBL44223 | 0.84 | RAB9A (0.37) | KMT2APTPN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |