Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44623 | 0.89 | FFAR1 (0.42) | HTTMAPK1KMT2ATSHR | |
| SCHEMBL44354 | 0.89 | HPGD (0.45) | HTTKMT2ATSHR | |
| SCHEMBL44314 | 0.88 | HDAC4 (0.42) | HTTTP53MAPT | |
| SCHEMBL45433 | 0.88 | GLA (0.37) | KMT2AMAPTGLA | |
| SCHEMBL44565 | 0.87 | HPGD (0.51) | HTTPKMTP53KMT2ATSHR | |
| SCHEMBL45068 | 0.87 | HPGD (0.38) | KMT2ATSHRHDAC1 | |
| SCHEMBL44310 | 0.87 | HPGD (0.50) | KMT2ATSHR | |
| SCHEMBL44594 | 0.86 | HTR1A (0.39) | HTTTP53KMT2AHDAC1HDAC2 | |
| SCHEMBL44304 | 0.85 | KCNH2 (0.43) | MAPK1TP53KMT2AMAPT | |
| SCHEMBL44277 | 0.85 | MEN1 (0.42) | TP53KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |