Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413065 | 0.90 | TXNRD1 (0.42) | TXNRD1OPRD1OPRM1PHLPP2KDM4E | |
| SCHEMBL4423408 | 0.90 | TXNRD1 (0.40) | TXNRD1OPRD1OPRM1PHLPP2KDM4E | |
| SCHEMBL4427273 | 0.88 | DNM1 (0.39) | TXNRD1OPRD1OPRM1PHLPP2 | |
| SCHEMBL4427994 | 0.87 | DNM1 (0.41) | TXNRD1OPRD1OPRM1PHLPP2 | |
| SCHEMBL4418406 | 0.87 | DNM1 (0.41) | TXNRD1OPRD1OPRM1PHLPP2 | |
| SCHEMBL4420951 | 0.86 | PHLPP2 (0.46) | TXNRD1CYP1A2SMN1; SMN2BLMPMP22 | |
| SCHEMBL4428186 | 0.84 | TXNRD1 (0.36) | TXNRD1OPRD1OPRM1 | |
| SCHEMBL4415201 | 0.82 | OPRD1 (0.36) | TXNRD1OPRD1OPRM1ALDH1A1 | |
| SCHEMBL4420950 | 0.81 | OPRD1 (0.36) | TXNRD1OPRD1OPRM1KDM4EALDH1A1 | |
| SCHEMBL4427266 | 0.80 | LSS (0.35) | TXNRD1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620475-B1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2009-11-11 | — | — | EP | disclosed |
| EP-1620475-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099262-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |