Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Azobenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 3/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azobenzene SCHEMBL29220906 | 1.00 | ALDH1A1 (0.71) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL1405620 | 0.97 | ALDH1A1 (0.75) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL1405621 | 0.97 | ALDH1A1 (0.75) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL31468903 | 0.87 | ALDH1A1 (0.92) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL11328908 | 0.84 | ALDH1A1 (0.86) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL11328902 | 0.84 | ALDH1A1 (0.86) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL32032 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL6703357 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL11124477 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1TSHRHSD17B10 | |
| Azobenzene SCHEMBL11878769 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116479483-A | Method and device for manufacturing high-precision metal microstructure by rapid additive of tip of light-operated liquid film | 江苏大学 | 2023-07-25 | — | — | CN | claimed |
| CN-113045780-B | Polymer material with light-regulated reversible morphology transformation and preparation method and application thereof | 杭州师范大学 | 2022-05-31 | — | — | CN | claimed |
| CN-113045780-A | Polymer material with light-regulated reversible morphology transformation and preparation method and application thereof | 杭州师范大学 | 2021-06-29 | — | — | CN | claimed |
| US-20090075318-A1 | USING PHOTO-RESPONSIVE SURFACTANTS TO REVERSIBLY CONTROL PROTEIN AGGREGATION WITH LIGHT ILLUMINATION | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-03-19 | — | — | US | claimed |
| CN-116479483-A | Method and device for manufacturing high-precision metal microstructure by rapid additive of tip of light-operated liquid film | 江苏大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-113045780-B | Polymer material with light-regulated reversible morphology transformation and preparation method and application thereof | 杭州师范大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-113045780-A | Polymer material with light-regulated reversible morphology transformation and preparation method and application thereof | 杭州师范大学 | 2021-06-29 | — | — | CN | disclosed |
| US-20090075318-A1 | USING PHOTO-RESPONSIVE SURFACTANTS TO REVERSIBLY CONTROL PROTEIN AGGREGATION WITH LIGHT ILLUMINATION | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075318-A1 | USING PHOTO-RESPONSIVE SURFACTANTS TO REVERSIBLY CONTROL PROTEIN AGGREGATION WITH LIGHT ILLUMINATION | CRYZ, STOM, CRYAA | ALDH1A1 4829/4885TDP1 2037/4885MAPK1 4312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.