Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442842 | 1.00 | GPR84 (0.48) | GPR84FFAR1MAPTTHRBFNTA | |
| SCHEMBL441393 | 0.93 | FNTA (0.55) | GPR84FFAR1MAPTTHRBFNTA | |
| SCHEMBL441392 | 0.93 | FNTA (0.55) | GPR84FFAR1MAPTTHRBFNTA | |
| SCHEMBL442893 | 0.93 | THRB (0.40) | GPR84FFAR1MAPTTHRBFNTA | |
| SCHEMBL442892 | 0.93 | THRB (0.40) | GPR84FFAR1MAPTTHRBFNTA | |
| SCHEMBL11591433 | 0.85 | FFAR1 (0.56) | GPR84FFAR1FFAR4PPARDALDH1A1 | |
| SCHEMBL7381683 | 0.85 | FFAR1 (0.56) | GPR84FFAR1FFAR4PPARDALDH1A1 | |
| SCHEMBL11331478 | 0.83 | FFAR1 (0.53) | GPR84FFAR1FFAR4PPARDALDH1A1 | |
| SCHEMBL3421013 | 0.83 | GPR84 (0.46) | GPR84FFAR1MAPTTHRBFNTA | |
| SCHEMBL6327851 | 0.81 | FFAR4 (0.67) | GPR84FFAR1MAPTFFAR4PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |