Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442893 | 1.00 | THRB (0.40) | THRBFNTAFNTBPGGT1BCA2 | |
| SCHEMBL442842 | 0.93 | GPR84 (0.48) | THRBFNTAFNTBPGGT1BGPR84 | |
| SCHEMBL442843 | 0.93 | GPR84 (0.48) | THRBFNTAFNTBPGGT1BGPR84 | |
| SCHEMBL441392 | 0.85 | FNTA (0.55) | THRBFNTAFNTBPGGT1BGPR84 | |
| SCHEMBL441393 | 0.85 | FNTA (0.55) | THRBFNTAFNTBPGGT1BGPR84 | |
| SCHEMBL790870 | 0.81 | CA2 (0.37) | THRBFNTAFNTBPGGT1BCA2 | |
| SCHEMBL11331478 | 0.78 | FFAR1 (0.53) | GPR84FFAR1AKR1B1FFAR4ALDH1A1 | |
| SCHEMBL241236 | 0.78 | CA2 (0.37) | THRBFNTAFNTBPGGT1BCA2 | |
| SCHEMBL7381683 | 0.77 | FFAR1 (0.56) | GPR84FFAR1AKR1B1FFAR4ALDH1A1 | |
| SCHEMBL11591433 | 0.77 | FFAR1 (0.56) | GPR84FFAR1AKR1B1FFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |