⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573678 | 0.79 | — | — | |
| SCHEMBL6544665 | 0.73 | — | — | |
| SCHEMBL6545188 | 0.73 | — | — | |
| SCHEMBL147664 | 0.71 | — | — | |
| Allylamine SCHEMBL9782543 | 0.71 | ALDH1A1 (0.50) | — | |
| SCHEMBL3513405 | 0.71 | — | — | |
| Bicarbonate SCHEMBL8069099 | 0.69 | GABRR1 (0.45) | — | |
| SCHEMBL285045 | 0.69 | — | — | |
| SCHEMBL444666 | 0.67 | — | — | |
| SCHEMBL8483541 | 0.67 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065265-A1 | ALPHA-2-DELTA LIGANDS FOR NON-RESTORATIVE SLEEP | PFIZER INC. | 2012-03-15 | — | — | US | disclosed |
| US-20090069427-A1 | ALPHA-2-DELTA LIGANDS FOR NON-RESTORATIVE SLEEP | PFIZER INC. | 2009-03-12 | — | — | US | disclosed |
| EP-1993529-A1 | ALPHA-2-DELTA LIGANDS FOR NON-RESTORATIVE SLEEP | Pfizer Products Inc. (US) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007102058-A1 | ALPHA-2-DELTA LIGANDS FOR NON-RESTORATIVE SLEEP | PFIZER PRODUCTS INC. (US) | 2007-09-13 | — | — | WO | disclosed |
| EP-0000107-B1 | METALLIC OR METALLISED ARTICLE COATED WITH A POLYPHENYLENE OXIDE FILM CARRYING REACTIVE GROUPS, ITS ELECTROCHEMICAL PREPARATION AND ITS USE | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1980-07-23 | — | — | EP | disclosed |
| EP-0000107-A1 | Metallic or metallised article coated with a polyphenylene oxide film carrying reactive groups, its electrochemical preparation and its use | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1978-12-20 | — | — | EP | disclosed |