Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.38 |
| ▸ | CDK9 | P50750 | 11/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418668 | 0.90 | PLA2G2A (0.43) | KDM4EALDH1A1KMT2ALIPE | |
| SCHEMBL3928219 | 0.87 | CNR1 (0.44) | HTR2CCCNT1CDK9ALDH1A1KMT2A | |
| SCHEMBL4429365 | 0.84 | CNR1 (0.36) | KMT2ALIPE | |
| SCHEMBL3927942 | 0.84 | CNR1 (0.41) | CCNT1CDK9GRIN1GRIN2B | |
| SCHEMBL14365682 | 0.80 | HTR2C (0.39) | HTR2CCCNT1CDK9GRIN1GRIN2B | |
| SCHEMBL4417085 | 0.79 | CNR1 (0.47) | — | |
| SCHEMBL4429813 | 0.79 | CNR1 (0.59) | ALDH1A1LIPE | |
| SCHEMBL13717249 | 0.78 | LMNA (0.40) | HTR2CCCNT1CDK9ALDH1A1KMT2A | |
| SCHEMBL4422551 | 0.78 | PLA2G2A (0.44) | ALDH1A1KMT2A | |
| SCHEMBL4425373 | 0.78 | CNR1 (0.40) | HTR2CLIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |