Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428607 | 0.90 | HTR2C (0.39) | LIPEKDM4EALDH1A1KMT2A | |
| SCHEMBL4422551 | 0.87 | PLA2G2A (0.44) | PLA2G2ACNR2NPC1RAB9AALDH1A1 | |
| SCHEMBL4424973 | 0.87 | MEN1 (0.46) | PLA2G2ANPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL4426908 | 0.87 | MEN1 (0.46) | PLA2G2ANPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL3930525 | 0.86 | PLA2G2A (0.44) | PLA2G2ACNR2NPC1RAB9AKDM4E | |
| SCHEMBL4428456 | 0.86 | MEN1 (0.46) | PLA2G2ANPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL4429365 | 0.85 | CNR1 (0.36) | LIPEKMT2ATSHR | |
| SCHEMBL4416088 | 0.84 | PLA2G2A (0.42) | PLA2G2ACNR2NPC1RAB9AALDH1A1 | |
| SCHEMBL4427086 | 0.84 | PLA2G2A (0.42) | PLA2G2ACNR2NPC1RAB9AALDH1A1 | |
| SCHEMBL4426602 | 0.84 | PLA2G2A (0.42) | PLA2G2ACNR2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |