Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797208 | 0.89 | MTNR1A (0.32) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3214187 | 0.77 | PTGS2 (0.37) | PTGS2MTNR1AMTNR1BHTR2CKCNH2 | |
| SCHEMBL1837381 | 0.72 | MTNR1A (0.36) | PTGS2MTNR1AMTNR1BHTR2CKCNH2 | |
| SCHEMBL1711854 | 0.71 | MTNR1A (0.35) | PTGS2MTNR1AMTNR1BHTR2CKCNH2 | |
| SCHEMBL1711953 | 0.70 | MTNR1A (0.39) | PTGS2MTNR1AMTNR1BHTR2C | |
| SCHEMBL14995338 | 0.68 | PTGS2 (0.36) | PTGS2MTNR1AMTNR1BHTR2CKCNH2 | |
| SCHEMBL1711943 | 0.68 | MTNR1A (0.42) | PTGS2MTNR1AMTNR1BHTR2C | |
| SCHEMBL3213697 | 0.67 | MTNR1A (0.40) | PTGS2MTNR1AMTNR1BHTR2C | |
| SCHEMBL1036797 | 0.67 | SLC2A1 (0.42) | MTNR1AMTNR1BHTR2CKCNH2 | |
| SCHEMBL3400408 | 0.66 | POLB (0.40) | PTGS2MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136807-A1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | Glaxo Group Limited (GB) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008125594-A1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | GLAXO GROUP LIMITED (GB) | 2008-10-23 | — | — | WO | disclosed |
| EP-1954697-A2 | PERI CONDENSED TRICYCLIC COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007081597-A2 | PERI CONDENSED TRICYCLIC COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-07-19 | — | — | WO | disclosed |