Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428675 | 0.89 | PTGS2 (0.35) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL1723874 | 0.68 | MTNR1A (0.36) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3228913 | 0.67 | MTNR1A (0.40) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3153644 | 0.67 | MTNR1A (0.41) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3216011 | 0.65 | SLC2A1 (0.33) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL1712054 | 0.65 | MTNR1A (0.38) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL3214187 | 0.62 | PTGS2 (0.37) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL1712055 | 0.61 | MTNR1A (0.40) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL1712179 | 0.60 | MTNR1A (0.39) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL1712093 | 0.59 | MTNR1A (0.31) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954697-A2 | PERI CONDENSED TRICYCLIC COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007081597-A2 | PERI CONDENSED TRICYCLIC COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-07-19 | — | — | WO | disclosed |