SCHEMBL4429045

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4418543	0.82	KMT2A (0.43)	CNR2HTR6POLBALDH1A1CYP1A2
	SCHEMBL4429023	0.76	HTR6 (0.55)	HTR6TOP2AHTT
	SCHEMBL4422242	0.75	HTT (0.40)	PKMCNR2HTR6POLBALDH1A1
	SCHEMBL4419370	0.74	HTR6 (0.59)	HTR6
	SCHEMBL4422283	0.74	HTR6 (0.39)	CNR2PTAFRHTR6POLBALDH1A1
	SCHEMBL4426419	0.74	HTR6 (0.51)	PKMHTR6POLBALDH1A1CYP1A2
	SCHEMBL4277397	0.71	PKM (0.38)	PKMHTR6
	SCHEMBL4421797	0.70	HTR6 (0.54)	HTR6
	SCHEMBL4430912	0.70	KDM4E (0.38)	CNR2HTR6POLBALDH1A1CYP1A2
	SCHEMBL4416995	0.68	HTR6 (0.50)	CNR2HTR6POLBALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.