Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897294 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2GAAALOX5ALDH1A1MAPK1 | |
| SCHEMBL3517296 | 0.82 | PLG (0.42) | HCAR2KMT2ASHBGNPSR1 | |
| SCHEMBL3517294 | 0.82 | PLG (0.42) | HCAR2KMT2ASHBGNPSR1 | |
| SCHEMBL17935800 | 0.82 | PLG (0.42) | HCAR2KMT2ASHBGNPSR1 | |
| SCHEMBL20178640 | 0.82 | PLG (0.42) | HCAR2KMT2ASHBGNPSR1 | |
| SCHEMBL8897299 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2GAAALOX5ALDH1A1MAPK1 | |
| SCHEMBL10270878 | 0.79 | ALOX5 (0.43) | SMN1; SMN2GAAALOX5ALDH1A1KMT2A | |
| SCHEMBL659048 | 0.79 | ALOX5 (0.43) | SMN1; SMN2GAAALOX5ALDH1A1KMT2A | |
| SCHEMBL8073959 | 0.79 | ALOX5 (0.43) | SMN1; SMN2GAAALOX5ALDH1A1KMT2A | |
| SCHEMBL16552322 | 0.78 | GAA (0.42) | SMN1; SMN2GAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115556441-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2023-01-03 | — | — | CN | disclosed |
| CN-115556446-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2023-01-03 | — | — | CN | disclosed |
| US-10730866-B2 | Indole derivatives and use thereof | PURDUE PHARMA L.P. (US) | 2020-08-04 | — | — | US | disclosed |
| CN-111386185-A | Decorative film and method for producing decorative molded body using same | 日本聚丙烯株式会社 | 2020-07-07 | — | — | CN | disclosed |
| WO-2015031396-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING MACROLIDE DIASTEREOMERS, METHODS OF THEIR SYNTHESIS AND THERAPEUTIC USES | REGENERON PHARMACEUTICALS, INC. (US) | 2015-03-05 | — | — | WO | disclosed |
| EP-2083045-A1 | Method and composition for control of crystallization rate of polyolefin resin, resin composition and resin molding | New Japan Chemical Co., Ltd. (JP) | 2009-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730866-B2 | Indole derivatives and use thereof | TRPC4, TRPV4, TRPV1 | SMN1; SMN2 780/4885GAA 4338/4885ALOX5 1519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.