Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL27519300 | 0.86 | ROCK2 (0.38) | SMN1; SMN2GAAMEN1KMT2APKM | |
| SCHEMBL8275656 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2GAAALDH1A1ALOX5MME | |
| SCHEMBL4429096 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2GAAALDH1A1MAPK1CHRM1 | |
| SCHEMBL5025923 | 0.80 | — | — | |
| SCHEMBL2427007 | 0.80 | — | — | |
| SCHEMBL6082609 | 0.80 | — | — | |
| SCHEMBL636865 | 0.80 | SHBG (0.40) | SHBG | |
| SCHEMBL31067200 | 0.79 | GAA (0.41) | SMN1; SMN2GAAALDH1A1DPP4DPP9 | |
| SCHEMBL31067102 | 0.78 | MAPT (0.45) | ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31067225 | 0.78 | GAA (0.40) | SMN1; SMN2GAAALDH1A1DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |