Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44711 | 0.90 | MAPT (0.43) | KMT2AKCNH2LMNA | |
| SCHEMBL44702 | 0.84 | KCNH2 (0.44) | KMT2AALDH1A1KCNH2L3MBTL1LMNA | |
| SCHEMBL44623 | 0.84 | FFAR1 (0.42) | KMT2ATSHRALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL45433 | 0.83 | GLA (0.37) | KMT2AALDH1A1 | |
| SCHEMBL44472 | 0.81 | HTT (0.40) | KMT2ATSHRMAPK1 | |
| SCHEMBL44354 | 0.80 | HPGD (0.45) | KMT2ATSHRALDH1A1HPGD | |
| SCHEMBL44365 | 0.80 | NOTUM (0.50) | KMT2ATSHRALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL44277 | 0.79 | MEN1 (0.42) | KMT2ATSHRALDH1A1KCNH2LMNA | |
| SCHEMBL44304 | 0.79 | KCNH2 (0.43) | KMT2AALDH1A1KCNH2LMNAMAPK1 | |
| SCHEMBL44310 | 0.79 | HPGD (0.50) | KMT2ATSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |