SCHEMBL4429309

SCHEMBL4429309

N#CSc1ccc(S(=O)(=O)O)cc1[N+](=O)[O-]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
HPGD P15428 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
GAA P10253 2/20 0.45
NSD2 O96028 1/20 0.45
PLCG1 P19174 1/20 0.45
DNMT1 P26358 1/20 0.45
CASP6 P55212 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CA2 P00918 5/20 0.45
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA9 Q16790 3/20 0.41
TXNRD1 Q16881 1/20 0.39
TXNRD3 Q86VQ6 1/20 0.39
TXNRD2 Q9NNW7 1/20 0.39
VCAM1 P19320 1/20 0.38
IDO1 P14902 1/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6515861 0.82 ALDH1A1 (0.55) ALDH1A1HPGDTDP1GAANSD2
SCHEMBL29350780 0.78 TXNRD1 (0.66) ALDH1A1HPGDTDP1GAATXNRD1
SCHEMBL466008 0.78 TXNRD1 (0.66) ALDH1A1HPGDTDP1GAATXNRD1
SCHEMBL28121409 0.76 TXNRD1 (0.64) ALDH1A1HPGDTDP1GAATXNRD1
SCHEMBL3407384 0.76 TDP1 (0.58) ALDH1A1TDP1L3MBTL1TXNRD1TXNRD3
SCHEMBL14984361 0.76 MAPT (0.57) ALDH1A1HPGDTDP1GAAL3MBTL1
SCHEMBL6089975 0.76 APEX1 (0.61) ALDH1A1HPGDCASP6KMT2AMEN1
SCHEMBL392626 0.75 HPGD (0.62) ALDH1A1HPGDTDP1GAANSD2
SCHEMBL1131324 0.74 CASP6 (0.67) ALDH1A1HPGDTDP1GAANSD2
SCHEMBL9358644 0.73 MAPT (0.56) ALDH1A1HPGDTDP1GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1563011-B1 MONO AZO DYES CLARIANT FINANCE BVI LTD (VG) 2009-01-14 EP disclosed
EP-1563011-A1 MONO AZO DYES Clariant Finance (BVI) Limited (VG) 2005-08-17 EP disclosed
WO-2004044057-A1 MONO AZO DYES CLARIANT INTERNATIONAL LTD (CH) 2004-05-27 WO disclosed