Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.71 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.70 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.70 |
| ▸ | APEX1 | P27695 | 2/20 | 0.70 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.70 |
| ▸ | FBP1 | P09467 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.70 |
| ▸ | RAD52 | P43351 | 1/20 | 0.70 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.70 |
| ▸ | TST | Q16762 | 1/20 | 0.70 |
| ▸ | PDE5A | O76074 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gossypetin SCHEMBL29419067 | 0.83 | MEN1 (1.00) | CDK1CCNB1MEN1KMT2AKDM4E | |
| Gossypetin SCHEMBL29929428 | 0.83 | MEN1 (1.00) | CDK1CCNB1MEN1KMT2AKDM4E | |
| Gossypetin SCHEMBL157033 | 0.83 | MEN1 (1.00) | CDK1CCNB1MEN1KMT2AKDM4E | |
| SCHEMBL29462912 | 0.82 | AMY1A (0.70) | CDK1CCNB1MEN1KMT2AKDM4E | |
| SCHEMBL15874292 | 0.82 | CDK1 (0.89) | CDK1CCNB1MEN1KMT2AKDM4E | |
| Gossypetin SCHEMBL16782915 | 0.81 | MEN1 (0.97) | CDK1CCNB1MEN1KMT2AKDM4E | |
| SCHEMBL15874555 | 0.81 | CDK1 (0.83) | CDK1CCNB1MEN1KMT2AKDM4E | |
| SCHEMBL2686819 | 0.81 | PDE5A (1.00) | CDK1CCNB1MEN1KMT2AKDM4E | |
| SCHEMBL13857095 | 0.79 | MEN1 (0.77) | CDK1CCNB1MEN1KMT2AKDM4E | |
| SCHEMBL29575800 | 0.79 | MEN1 (0.77) | CDK1CCNB1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558922-B1 | IDENTIFYING THERAPEUTIC COMPOUNDS BASED ON THEIR PHYSICAL-CHEMICAL PROPERTIES | AMPERE LIFE SCIENCES INC (US) | 2013-02-27 | — | — | EP | disclosed |
| US-20090162890-A1 | IDENTIFYING THERAPEUTIC COMPOUNDS BASED ON THEIR PHYSICAL-CHEMICAL PROPERTIES | EDISON PHARMACEUTICALS, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| US-20090163529-A1 | IDENTIFYING THERAPEUTIC COMPOUNDS BASED ON THEIR PHYSICAL-CHEMICAL PROPERTIES | EDISON PHARMACEUTICALS, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| US-7491312-B2 | Identifying therapeutic compounds based on their physical-chemical properties | EDISON PHARMACEUTICALS, INC. (US) | 2009-02-17 | — | — | US | disclosed |
| EP-1558922-A4 | IDENTIFYING THERAPEUTIC COMPOUNDS BASED ON THEIR PHYSICAL-CHEMICAL PROPERTIES | EDISON PHARMACEUTICALS INC (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1558922-A2 | IDENTIFYING THERAPEUTIC COMPOUNDS BASED ON THEIR PHYSICAL-CHEMICAL PROPERTIES | Galileo Pharmaceuticals, Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| US-20040105817-A1 | Identifying therapeutic compounds based on their physical-chemical properties | PTC THERAPEUTICS, INC. | 2004-06-03 | — | — | US | disclosed |
| WO-2004042353-A2 | IDENTIFYING THERAPEUTIC COMPOUNDS BASED ON THEIR PHYSICAL-CHEMICAL PROPERTIES | GALILEO PHARMACEUTICALS, INC. (US) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040105817-A1 | Identifying therapeutic compounds based on their physical-chemical properties | ABCG2, MRPS34, MRPS35 | CDK1 4289/4885CCNB1 3416/4885MEN1 3081/4885 |
| US-20090163529-A1 | IDENTIFYING THERAPEUTIC COMPOUNDS BASED ON THEIR PHYSICAL-CHEMICAL PROPERTIES | ABCG2, MRPS34, MRPS35 | CDK1 4289/4885CCNB1 3416/4885MEN1 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.