Propylene Glycol Monostearate

Propylene Glycol Monostearate

SCHEMBL4429462

CCCCCCCC.CCCCCCCCCCCCCCCCCC(=O)OCC(C)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 1.00
LMNA P02545 4/20 0.69
KDM4E B2RXH2 1/20 0.69
DUSP3 P51452 1/20 0.69
MEN1 O00255 1/20 0.69
KMT2A Q03164 1/20 0.69
ALDH1A1 P00352 1/20 0.66
DGKA P23743 2/20 0.62
PRKCA P17252 3/20 0.60
PRKCE Q02156 1/20 0.60
PRKCQ Q04759 1/20 0.60
PRKCD Q05655 1/20 0.60
LPAR6 P43657 1/20 0.59
LPAR1 Q92633 1/20 0.59
LPAR4 Q99677 1/20 0.59
LPAR5 Q9H1C0 1/20 0.59
LPAR2 Q9HBW0 1/20 0.59
LPAR3 Q9UBY5 1/20 0.59
ENPP2 Q13822 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2115586 1.00 MAPT (1.00) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL141668 1.00 MAPT (1.00) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL1730481 1.00 MAPT (1.00) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL29649070 1.00 MAPT (1.00) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL180498 1.00 MAPT (1.00) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL629794 1.00 MAPT (1.00) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL26974 1.00 MAPT (1.00) MAPTLMNAKDM4EDUSP3MEN1
Propylene Glycol Monostearate SCHEMBL35521 1.00 MAPT (1.00) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL16458 1.00 MAPT (1.00) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL1173237 1.00 MAPT (1.00) MAPTLMNAKDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8496939-B2 An adjuvant is used in vaccine formulation, comprising a polymeric emulsifier Arlacel\" or ATLOX\"; stable, low viscosity INTERVET INTERNATIONAL B.V. (NL) 2013-07-30 US disclosed
EP-1367997-B1 INJECTABLE WATER-IN-OIL EMULSIONS INTERVET INT BV (NL) 2009-08-05 EP disclosed
US-20080118538-A1 OIL DISPERSION OF POWDER BEING SURFACE-TREATED WITH SPECIFIC HALF ESTER OIL, AND COSMETIC COMPOSITION CONTAINING THE SAME MIYOSHI KASEI, INC. (JP) 2008-05-22 US disclosed
EP-1881039-A1 OIL DISPERSION OF POWDER BEING SURFACE-TREATED WITH SPECIFIC ACIDIC ESTER OIL, AND COSMETIC COMPOSITION CONTAINING THE SAME Miyoshi Kasei, Inc. (JP) 2008-01-23 EP disclosed
US-20040071716-A1 Injectable water-in-oil emulsions INTERVET INTERNATIONAL B.V. (NL) 2004-04-15 US disclosed
EP-1367997-A1 INJECTABLE WATER-IN-OIL EMULSIONS Akzo Nobel N.V. (NL) 2003-12-10 EP disclosed
WO-2002067899-A1 INJECTABLE WATER-IN-OIL EMULSIONS AKZO NOBEL N.V. (NL) 2002-09-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040071716-A1 Injectable water-in-oil emulsions ALOX15, ALOX12, ALOX5 MAPT 3856/4885LMNA 1361/4885KDM4E 2875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.