Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.51 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.51 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.51 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.51 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.51 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.51 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.51 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484563 | 1.00 | NR1I2 (0.67) | NR1I2NR1H4RORCATP1A1ATP1B1 | |
| SCHEMBL29935011 | 1.00 | NR1I2 (0.67) | NR1I2NR1H4RORCATP1A1ATP1B1 | |
| SCHEMBL4429572 | 1.00 | NR1I2 (0.67) | NR1I2NR1H4RORCATP1A1ATP1B1 | |
| SCHEMBL29934972 | 0.89 | NR1H4 (0.71) | NR1I2NR1H4RORCATP1A1ATP1B1 | |
| SCHEMBL30106442 | 0.88 | NR1I2 (0.62) | NR1I2NR1H4RORCATP1A1ATP1B1 | |
| SCHEMBL4303282 | 0.88 | USP2 (0.56) | NR1I2NR1H4RORCATP1A1ATP1B1 | |
| SCHEMBL337078 | 0.88 | USP2 (0.56) | NR1I2NR1H4RORCATP1A1ATP1B1 | |
| SCHEMBL7512355 | 0.88 | USP2 (0.56) | NR1I2NR1H4RORCATP1A1ATP1B1 | |
| SCHEMBL5095966 | 0.88 | USP2 (0.56) | NR1I2NR1H4RORCATP1A1ATP1B1 | |
| SCHEMBL26642363 | 0.88 | USP2 (0.56) | NR1I2NR1H4RORCATP1A1ATP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863470-B2 | Linear polyethylenimine-sterol conjugates for gene delivery | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2011-01-04 | — | — | US | claimed |
| US-20070154447-A1 | Linear polyethylenimine-sterol conjugates for gene delivery | FURGESON DARIN Y | 2007-07-05 | — | — | US | claimed |
| US-7183263-B2 | Linear polyethylenimine-sterol conjugates for gene delivery | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2007-02-27 | — | — | US | claimed |
| US-20040137050-A1 | Linear polyethylenimine-sterol conjugates for gene delivery | THE UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2004-07-15 | — | — | US | claimed |
| US-11918770-B2 | Implants for localized drug delivery and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-03-05 | — | — | US | disclosed |
| US-20230263182-A1 | COMPOSITIONS ISOLATED FROM DATE PALM TREE | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (IL) | 2023-08-24 | — | — | US | disclosed |
| US-20220184362-A1 | Implants for Localized Drug Delivery and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-16 | — | — | US | disclosed |
| US-11324935-B2 | Implants for localized drug delivery and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-10 | — | — | US | disclosed |
| US-10912933-B2 | Implants for localized drug delivery and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-09 | — | — | US | disclosed |
| EP-3183026-B1 | IMPLANTS FOR LOCALIZED DRUG DELIVERY AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2019-10-30 | — | — | EP | disclosed |
| US-20190184145-A1 | Implants for Localized Drug Delivery and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-06-20 | — | — | US | disclosed |
| US-20170224970-A1 | Implants for Localized Drug Delivery and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-10 | — | — | US | disclosed |
| EP-2136856-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY | Miv Therapeutics Inc. (CA) | 2009-12-30 | — | — | EP | disclosed |
| US-20080181928-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY | MIV THERAPEUTICS, INC. (CA) | 2008-07-31 | — | — | US | disclosed |
| WO-2008077247-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING CHOLESTEROL | MIV THERAPEUTICS INC. (CA) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008077248-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY | MIV THERAPEUTICS INC. (CA) | 2008-07-03 | — | — | WO | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| US-20070154447-A1 | Linear polyethylenimine-sterol conjugates for gene delivery | FURGESON DARIN Y | 2007-07-05 | — | — | US | disclosed |
| US-7183263-B2 | Linear polyethylenimine-sterol conjugates for gene delivery | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2007-02-27 | — | — | US | disclosed |
| US-20040137050-A1 | Linear polyethylenimine-sterol conjugates for gene delivery | THE UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | NR1I2 47/4885NR1H4 32/4885RORC 269/4885 |
| US-20080181928-A1 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES FOR LIPOSOME DELIVERY | LIPA, SGMS2, SGMS1 | NR1I2 4100/4885NR1H4 3333/4885RORC 2974/4885 |
| US-20040137050-A1 | Linear polyethylenimine-sterol conjugates for gene delivery | LDLR, CETP, CYP11A1 | NR1I2 834/4885NR1H4 58/4885RORC 1925/4885 |
| US-20070154447-A1 | Linear polyethylenimine-sterol conjugates for gene delivery | LDLR, CETP, CYP11A1 | NR1I2 834/4885NR1H4 58/4885RORC 1925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.