Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 4/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.51 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.51 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.51 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.51 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.51 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.51 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.51 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 4/20 | 0.47 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5095966 | 1.00 | USP2 (0.56) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL26642363 | 1.00 | USP2 (0.56) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7512355 | 1.00 | USP2 (0.56) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4303282 | 1.00 | USP2 (0.56) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7249459 | 0.88 | NR1I2 (0.50) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4429572 | 0.88 | NR1I2 (0.67) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4429574 | 0.88 | NR1I2 (0.67) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31484563 | 0.88 | NR1I2 (0.67) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29935011 | 0.88 | NR1I2 (0.67) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7246364 | 0.87 | NR1H4 (0.50) | USP2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040048838-A1 | Meiosis regulating compounds | GRONVALD FREDERIK CHRISTIAN (DK) | 2004-03-11 | — | — | US | claimed |
| US-20020013302-A1 | Meiosis regulating compounds | NOVO NORDISK A/S (DK) | 2002-01-31 | — | — | US | claimed |
| EP-0857173-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-08-12 | — | — | EP | claimed |
| WO-1997000884-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | claimed |
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS INC (US) | 2025-10-16 | — | — | US | disclosed |
| EP-4522646-A2 | APOE LIPOPROTEIN SYSTEMS | Kisbee Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220387-A2 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-8097632-B2 | Blocking hedgehog protein transduction signal passageway using alkaloid steroid | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2012-01-17 | — | — | US | disclosed |
| US-20100273818-A1 | INHIBITORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2010-10-28 | — | — | US | disclosed |
| US-20080058298-A1 | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE | 2008-03-06 | — | — | US | disclosed |
| US-7291626-B1 | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto | JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2007-11-06 | — | — | US | disclosed |
| US-20060142245-A1 | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto | JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2006-06-29 | — | — | US | disclosed |
| EP-0773250-B1 | Chiral dianhydro hexite derivative containing liquid-crystalline organosiloxanes | CONSORTIUM ELEKTROCHEM IND (DE) | 1999-01-27 | — | — | EP | disclosed |
| EP-0857173-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-08-12 | — | — | EP | disclosed |
| US-5788880-A | Liquid-crystalline organosiloxanes containing chiral dianhydrohexitol derivatives | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1998-08-04 | — | — | US | disclosed |
| US-5716777-A | REGULATING MEIOSIS IN MAMMALIAN GERM CELL BY ADMINISTERING SPECIFIED STEROL IN VITRO | NOVO NORDISK A/S (DK) | 1998-02-10 | — | — | US | disclosed |
| US-5695680-A | Liquid crystalline doristerol-containing organosiloxanes | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1997-12-09 | — | — | US | disclosed |
| EP-0773250-A1 | Chiral dianhydro hexite derivative containing liquid-crystalline organosiloxanes | Consortium für elektrochemische Industrie GmbH (DE) | 1997-05-14 | — | — | EP | disclosed |
| WO-1997000884-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | disclosed |
| EP-0664826-B1 | LIQUID CRYSTALLINE ORGANOSILOXANES CONTAINING DORISTEROL | CONSORTIUM ELEKTROCHEM IND (DE) | 1996-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273818-A1 | INHIBITORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO | SHH, GLI1, SMO | USP2 1940/4885MEN1 923/4885KMT2A 3380/4885 |
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | APOB, APOL1, LDLR | USP2 2046/4885MEN1 3385/4885KMT2A 4008/4885 |
| US-20080058298-A1 | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto | SHH, GLI1, SMO | USP2 1993/4885MEN1 1092/4885KMT2A 3422/4885 |
| US-20020013302-A1 | Meiosis regulating compounds | CYP11A1, NR5A1, MNS1 | USP2 4073/4885MEN1 851/4885KMT2A 3180/4885 |
| US-20060142245-A1 | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto | SHH, GLI1, SMO | USP2 1940/4885MEN1 923/4885KMT2A 3380/4885 |
| US-20040048838-A1 | Meiosis regulating compounds | CYP11A1, NR5A1, MNS1 | USP2 4073/4885MEN1 851/4885KMT2A 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.