Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26018559 | 0.92 | NPSR1 (0.54) | NPSR1PKMMAPTMEN1KMT2A | |
| SCHEMBL606866 | 0.88 | NPSR1 (0.62) | NPSR1PKMMAPTMEN1KMT2A | |
| SCHEMBL8551044 | 0.83 | MEN1 (0.59) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL280126 | 0.82 | FABP7 (0.58) | PKMKMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6666657 | 0.82 | FABP7 (0.58) | PKMKMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10917021 | 0.82 | FABP7 (0.58) | PKMKMT2AALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8550696 | 0.82 | MEN1 (0.58) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL20625039 | 0.82 | ALDH1A1 (0.47) | NPSR1PKMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13287204 | 0.81 | SMN1; SMN2 (0.57) | NPSR1PKMMAPTMEN1KMT2A | |
| SCHEMBL3409075 | 0.81 | SMN1; SMN2 (0.57) | NPSR1PKMMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072643-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-11 | — | — | WO | disclosed |