SCHEMBL4429697

SCHEMBL4429697

O=C(O)c1nc(C(=O)O)c(C(=O)O)s1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
HPGD P15428 1/20 0.38
CDC7 O00311 1/20 0.34
DBF4 Q9UBU7 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
MAPT P10636 1/20 0.33
GPR35 Q9HC97 3/20 0.32
LDHA P00338 1/20 0.32
LDHB P07195 1/20 0.32
KDM4E B2RXH2 3/20 0.32
RAB9A P51151 2/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
ALOX15 P16050 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6003366 0.78 SMN1; SMN2 (0.41) ALDH1A1TSHRHPGDCDC7DBF4
SCHEMBL4883695 0.74 ALDH1A1 (0.45) ALDH1A1TSHRHPGDSMN1; SMN2MAPT
SCHEMBL3655946 0.74 ALDH1A1 (0.61) ALDH1A1TSHRHPGDSMN1; SMN2MAPT
SCHEMBL12186535 0.74 ALDH1A1 (0.46) ALDH1A1HPGDSMN1; SMN2MAPTKDM4E
SCHEMBL5521979 0.70 ALDH1A1 (0.37) ALDH1A1TSHRHPGDSMN1; SMN2KDM4E
SCHEMBL14773411 0.70 ALDH1A1 (0.37) ALDH1A1TSHRHPGDSMN1; SMN2KDM4E
SCHEMBL12186582 0.70 ALDH1A1 (0.33) ALDH1A1TSHRHPGD
SCHEMBL2169300 0.69 TSHR (0.33) ALDH1A1TSHRHPGDCDC7DBF4
SCHEMBL6003698 0.67 ALDH1A1 (0.44) ALDH1A1TSHRHPGDSMN1; SMN2MAPT
SCHEMBL2810460 0.67 SMN1; SMN2 (0.67) ALDH1A1HPGDCDC7DBF4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024223872-A1 PROCESS GIVAUDAN SA (CH) 2024-10-31 WO disclosed
US-20190106722-A1 Production of Glycosylated Melanin Precursors in Recombinant Hosts EVOLVA SA (CH) 2019-04-11 US disclosed
WO-2017182373-A1 PRODUCTION OF GLYCOSYLATED MELANIN PRECURSORS IN RECOMBINANT HOSTS EVOLVA SA (CH) 2017-10-26 WO disclosed
US-8652827-B2 Radiosynthesis as an alternative energy utilization process in melanized organisms and uses thereof ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2014-02-18 US disclosed
US-20090328258-A1 Radiosynthesis as an Alternative Energy Utilization Process in Melanized Organisms and Uses Thereof ALBERT EINSTEIN COLLEGE OF MEDICINE 2009-12-31 US disclosed
WO-2007117453-A2 RADIOSYNTHESIS AS AN ALTERNATIVE ENERGY UTILIZATION PROCESS IN MELANIZED ORGANISMS AND USES THEREOF ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2007-10-18 WO disclosed