SCHEMBL4883695

SCHEMBL4883695

Cc1nc(C(=O)O)c(C(=O)O)s1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
TSHR P16473 1/20 0.45
RAB9A P51151 6/20 0.43
SMN1; SMN2 Q16637 5/20 0.43
NPC1 O15118 4/20 0.43
RECQL P46063 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 4/20 0.38
GAA P10253 2/20 0.38
PKM P14618 2/20 0.38
HCAR2 Q8TDS4 1/20 0.38
KMT2A Q03164 1/20 0.37
HTT P42858 1/20 0.37
MAPT P10636 2/20 0.37
TP53 P04637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
POLB P06746 1/20 0.36
LDHA P00338 1/20 0.35
PIK3CD O00329 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1432390 0.87 ALDH1A1 (0.38) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL9199229 0.79 ALDH1A1 (0.57) ALDH1A1HPGDTSHRRAB9ANPC1
SCHEMBL9197824 0.79 ALDH1A1 (0.57) ALDH1A1HPGDTSHRSMN1; SMN2NPC1
SCHEMBL286332 0.79 ALDH1A1 (0.63) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL2216614 0.79 SMN1; SMN2 (0.40) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL9204332 0.78 ALDH1A1 (0.41) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL9198002 0.78 ALDH1A1 (0.44) ALDH1A1HPGDRAB9ASMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL9528992 0.77 ALDH1A1 (0.61) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL28211661 0.77 ALDH1A1 (0.45) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2
SCHEMBL6003366 0.76 SMN1; SMN2 (0.41) ALDH1A1HPGDTSHRRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735426-A1 HETEROAROMATIC DHODH INHIBITORS Immunic AG (DE) 2026-05-06 EP disclosed
WO-2025003402-A1 HETEROAROMATIC DHODH INHIBITORS IMMUNIC AG (DE) 2025-01-02 WO disclosed
EP-2569375-B1 MODIFIED PIGMENTS CABOT CORP (US) 2017-11-22 EP disclosed
US-8771411-B2 Modified pigments CABOT CORPORATION (US) 2014-07-08 US disclosed
WO-2010013222-A1 PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2010-02-04 WO disclosed
US-20080214533-A1 Cyclic Iminocarbamates And Their Use BAYER HEALTHCARE AG (DE) 2008-09-04 US disclosed
EP-1819701-A1 CYCLIC IMINOCARBAMATES AND USE THEREOF Bayer HealthCare AG (DE) 2007-08-22 EP disclosed
WO-2006058630-A1 CYCLIC IMINOCARBAMATES AND USE THEREOF BAYER HEALTHCARE AG (DE) 2006-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214533-A1 Cyclic Iminocarbamates And Their Use F2, UQCRB, F12 ALDH1A1 348/4885HPGD 593/4885TSHR 1635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.