SCHEMBL6003366

SCHEMBL6003366

O=C(O)c1nc(-c2nc(C(=O)O)c(C(=O)O)s2)sc1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.41
KDM4E B2RXH2 5/20 0.40
RAB9A P51151 3/20 0.40
GAA P10253 1/20 0.40
CDC7 O00311 2/20 0.39
DBF4 Q9UBU7 2/20 0.39
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
HPGD P15428 2/20 0.39
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.34
LDHA P00338 1/20 0.33
LDHB P07195 1/20 0.33
XDH P47989 1/20 0.32
PKM P14618 1/20 0.31
TARBP2 Q15633 1/20 0.31
ALOX15 P16050 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2810460 0.82 SMN1; SMN2 (0.67) SMN1; SMN2KDM4ERAB9AGAACDC7
SCHEMBL4429697 0.78 ALDH1A1 (0.38) SMN1; SMN2KDM4ERAB9AGAACDC7
SCHEMBL12186535 0.76 ALDH1A1 (0.46) SMN1; SMN2KDM4ERAB9AALDH1A1HPGD
SCHEMBL4883695 0.76 ALDH1A1 (0.45) SMN1; SMN2KDM4ERAB9AGAAALDH1A1
SCHEMBL11051000 0.72 KDM4E (0.46) SMN1; SMN2KDM4ERAB9AGAAALDH1A1
SCHEMBL14773411 0.72 ALDH1A1 (0.37) SMN1; SMN2KDM4ERAB9AGAAALDH1A1
SCHEMBL12186582 0.72 ALDH1A1 (0.33) ALDH1A1TSHRHPGD
SCHEMBL5521979 0.72 ALDH1A1 (0.37) SMN1; SMN2KDM4ERAB9AGAAALDH1A1
SCHEMBL12405035 0.67 ALDH1A1 (0.40) SMN1; SMN2KDM4EALDH1A1TSHRKMT2A
SCHEMBL22382 0.65 ALDH1A1 (0.55) SMN1; SMN2KDM4EALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7092608-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-15 US disclosed
US-7082244-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-25 US disclosed
US-20060159413-A1 POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-20 US disclosed
US-20040197064-A1 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2004-10-07 US disclosed