SCHEMBL4430156

SCHEMBL4430156

C=P(Oc1ccccc1CC)(Oc1ccccc1CC)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 7/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HPGD P15428 1/20 0.38
ATM Q13315 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CXCL8 P10145 1/20 0.36
KDM4E B2RXH2 2/20 0.36
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 1/20 0.35
NISCH Q9Y2I1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779558 0.80 L3MBTL1 (0.52) L3MBTL1HTTMAPTNPSR1HPGD
SCHEMBL27826156 0.80 MEN1 (0.50) L3MBTL1HTTMAPTNPSR1HPGD
SCHEMBL779559 0.77 L3MBTL1 (0.46) L3MBTL1HTTMAPTNPSR1HPGD
SCHEMBL29636357 0.75 L3MBTL1 (0.50) L3MBTL1HTTMAPTNPSR1HPGD
SCHEMBL1592230 0.75 L3MBTL1 (0.50) L3MBTL1HTTMAPTNPSR1HPGD
SCHEMBL28173346 0.75 L3MBTL1 (0.65) L3MBTL1HTTMAPTNPSR1MEN1
SCHEMBL778836 0.73 L3MBTL1 (0.48) L3MBTL1HTTMAPTNPSR1HPGD
SCHEMBL1591871 0.73 L3MBTL1 (0.48) L3MBTL1HTTMAPTNPSR1HPGD
SCHEMBL5852162 0.72 L3MBTL1 (0.47) L3MBTL1HTTMAPTNPSR1HPGD
SCHEMBL2150397 0.72 L3MBTL1 (0.47) L3MBTL1HTTMAPTNPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114568-B1 PHOSPHONITE-CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES EASTMAN CHEM CO (US) 2013-05-08 EP disclosed
EP-2135064-A1 AMPEROMETRIC BIOSENSOR FOR HISTAMINE DETERMINATION Universiti Putra Malaysia (MY) 2009-12-23 EP disclosed
EP-2114568-A1 PHOSPHONITE-CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES Eastman Chemical Company (US) 2009-11-11 EP disclosed
WO-2008115044-A1 AMPEROMETRIC BIOSENSOR FOR HISTAMINE DETERMINATION UNIVERSITI PUTRA MALAYSIA (MY) 2008-09-25 WO disclosed
WO-2008088495-A1 PHOSPHONITE-CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES EASTMAN CHEMICAL COMPANY (US) 2008-07-24 WO disclosed