SCHEMBL1591871

SCHEMBL1591871

CCc1ccccc1OP(=S)(Oc1ccccc1CC)Oc1ccccc1CC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.48
MAPT P10636 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
HPGD P15428 1/20 0.42
ATM Q13315 1/20 0.42
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 1/20 0.39
NISCH Q9Y2I1 1/20 0.38
HTT P42858 1/20 0.37
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1605196 0.91 L3MBTL1 (0.42) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL29829807 0.84 HTR1A (0.41) NISCHADRA2AADRA2BADRA2CSLC6A2
SCHEMBL258522 0.84 HTR1A (0.41) NISCHADRA2AADRA2BADRA2CSLC6A2
Zinc Ion SCHEMBL11465911 0.82 L3MBTL1 (0.44) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL29829780 0.81 THRA (0.47)
SCHEMBL258596 0.81 THRA (0.47)
SCHEMBL11077079 0.81 L3MBTL1 (0.43) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL5552769 0.81 L3MBTL1 (0.43) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL1592230 0.81 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL29636357 0.81 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1HPGDATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8901052-B2 Transmission oil composition for automobile NISSAN MOTOR CO., LTD. (JP) 2014-12-02 US disclosed
EP-1405897-B1 USE OF A TRANSMISSION OIL FOR AUTOMOBILES NISSAN MOTOR (JP) 2013-06-26 EP disclosed
US-20110092402-A1 TRANSMISSION OIL COMPOSITION FOR AUTOMOBILE SAGAWA TAKUMARU 2011-04-21 US disclosed
US-20080058233-A1 Mineral oil combined with zinc hydrocarbyldithiophosphate, triaryl phosphate and/or triaryl thiophosphate; electric or hybrid vehicles; insulating, cooling, lubricity NISSAN MOTOR CO., LTD. (JP) 2008-03-06 US disclosed
US-7307048-B2 comprises mineral oil, and phosphate compound selected a zinc dithiophosphate having hydrocarbon group, a triaryl phosphate, and triaryl thiophosphate; for electric motors; improved insulation, cooling and lubricity NISSAN MOTOR CO., LTD. (JP) 2007-12-11 US disclosed
US-20040209786-A1 comprises mineral oil, and phosphate compound selected a zinc dithiophosphate having hydrocarbon group, a triaryl phosphate, and triaryl thiophosphate; for electric motors; improved insulation, cooling and lubricity NIPPON OIL CORPORATION (JP) 2004-10-21 US disclosed
EP-1405897-A1 TRANSMISSION OIL COMPOSITION FOR AUTOMOBILE Nissan Motor Co., Ltd. (JP) 2004-04-07 EP disclosed