SCHEMBL4430284

SCHEMBL4430284

O=C(O)c1cccc(C2c3ccccc3-c3ccccc32)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.50
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
POLB P06746 1/20 0.45
HSP90AA1 P07900 1/20 0.45
MAPT P10636 1/20 0.45
VCP P55072 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA6 P23280 1/20 0.44
CA9 Q16790 1/20 0.44
DAO P14920 1/20 0.43
TSHR P16473 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
TTR P02766 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28242400 0.83 TDP1 (0.40) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL1689377 0.83 MAPT (0.60) KMOKMT2AMEN1KDM4EALDH1A1
SCHEMBL27861842 0.82 HTR2B (0.37) L3MBTL1
Terephthalic Acid SCHEMBL5798363 0.82 TTR (0.41) KMOKMT2AMEN1KDM4EALDH1A1
Terephthalic Acid SCHEMBL5797947 0.82 CA12 (0.46) KMT2AMEN1KDM4EALDH1A1GAA
SCHEMBL28851605 0.79 HTR2A (0.44) ALDH1A1MAPTL3MBTL1CA1CA2
SCHEMBL28825858 0.78 TTR (0.50) KMT2AMEN1KDM4EALDH1A1GAA
SCHEMBL27892789 0.76 KMT2A (0.47) KMT2AMEN1KDM4EALDH1A1GAA
SCHEMBL5798408 0.76 ALDH1A1 (0.43) KMT2AMEN1KDM4EALDH1A1GAA
Isophthalic Acid SCHEMBL9679148 0.75 DAO (0.62) KMOKMT2AMEN1POLBHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107429033-B Resin composition and optical lens 大阪燃气化学有限公司 2020-11-24 CN disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed