Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27892789 | 0.90 | KMT2A (0.47) | CA12CA1CA2CA6CA9 | |
| Terephthalic Acid SCHEMBL5798363 | 0.89 | TTR (0.41) | MEN1KMT2AKDM4ETTRCES2 | |
| SCHEMBL29266726 | 0.82 | CA12 (0.44) | CA12CA1CA2CA6CA9 | |
| SCHEMBL4430284 | 0.82 | KMO (0.50) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL28378402 | 0.79 | CA12 (0.73) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL8766630 | 0.79 | CA12 (0.73) | CA12CA1CA2CA6CA9 | |
| Terephthalic Acid SCHEMBL11040369 | 0.79 | CA12 (0.73) | CA12CA1CA2CA6CA9 | |
| SCHEMBL918436 | 0.79 | KMT2A (0.61) | CA12CA1CA2CA9CA3 | |
| Terephthalic Acid SCHEMBL440232 | 0.78 | CA12 (0.72) | CA12CA1CA2CA6CA9 | |
| Terephthalic Acid SCHEMBL9634104 | 0.78 | CA12 (0.72) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030873-A1 | POLYAMIDE, FILM, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2006-03-23 | — | — | WO | disclosed |