SCHEMBL28825858

SCHEMBL28825858

O=C(O)c1cc(C(=O)O)cc(C2c3ccccc3C(=O)c3ccccc32)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 5/20 0.50
EDNRB P24530 4/20 0.49
EDNRA P25101 4/20 0.49
PTPRC P08575 2/20 0.45
ALDH1A1 P00352 3/20 0.42
KMT2A Q03164 3/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 2/20 0.42
POLB P06746 2/20 0.42
CHEK1 O14757 1/20 0.42
LMNA P02545 1/20 0.42
BCHE P06276 1/20 0.42
HSP90AA1 P07900 1/20 0.42
HSP90AB1 P08238 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4430284 0.78 KMO (0.50) TTRPTPRCALDH1A1KMT2AKDM4E
SCHEMBL3135177 0.78 CYP1A2 (0.58) EDNRBEDNRAALDH1A1KMT2AKDM4E
SCHEMBL27770267 0.72 KMT2A (0.63) EDNRBEDNRAKMT2AKDM4EMEN1
Terephthalic Acid SCHEMBL5798363 0.71 TTR (0.41) TTRPTPRCALDH1A1KMT2AKDM4E
Terephthalic Acid SCHEMBL5797947 0.71 CA12 (0.46) TTRPTPRCALDH1A1KMT2AKDM4E
SCHEMBL25028023 0.71 LMNA (0.54) EDNRBEDNRAPTPRCALDH1A1KMT2A
Anthraquinone SCHEMBL2542462 0.69 TSHR (0.70) TTRPTPRCALDH1A1KMT2AMEN1
SCHEMBL28201245 0.69 CYP1A2 (0.41) EDNRBEDNRAKMT2AKDM4EMEN1
SCHEMBL10933413 0.69 EDNRB (0.50) EDNRBEDNRAALDH1A1LMNACYP3A4
SCHEMBL6906665 0.69 EDNRB (0.66) TTREDNRBEDNRAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105237337-A Novel synthesis method for 5-[10-(9-carbosyl anthryl)]-isophthalic acid UNIV ZUNYI MEDICAL 2016-01-13 CN disclosed
CN-105237337-A Novel synthesis method for 5-[10-(9-carbosyl anthryl)]-isophthalic acid UNIV ZUNYI MEDICAL 2016-01-13 CN disclosed