Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 2/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502967 | 0.84 | MEP1B (0.35) | PGDMEP1BMMP2CA1CA2 | |
| SCHEMBL4555303 | 0.81 | MMP1 (0.41) | MMP2CA1CA2MMP1MMP3 | |
| SCHEMBL7763537 | 0.81 | MEP1B (0.37) | PGDMEP1BMMP2CA1CA2 | |
| SCHEMBL14502966 | 0.81 | MEP1B (0.37) | PGDMEP1BMMP2CA1CA2 | |
| SCHEMBL4554492 | 0.70 | MEP1B (0.50) | MEP1BMMP2MMP1MMP3MMP9 | |
| SCHEMBL4077155 | 0.67 | KDM4E (0.32) | — | |
| SCHEMBL16792099 | 0.65 | FNTA (0.39) | PGDMMP2CA1CA2CA9 | |
| SCHEMBL4441598 | 0.63 | MEP1B (0.40) | PGDMEP1BMMP2CA1CA2 | |
| SCHEMBL4442494 | 0.62 | MMP1 (0.45) | MMP2CA1CA2MMP1MMP3 | |
| SCHEMBL10482413 | 0.62 | TET2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4391747-B2 | — | — | 2009-12-24 | — | — | JP | claimed |
| JP-2004532837-A | — | — | 2004-10-28 | — | — | JP | claimed |
| US-20040176424-A1 | Insecticide and method of controlling insects | NUFARM AUSTRALIA LIMITED (AU) | 2004-09-09 | — | — | US | claimed |
| EP-1385379-A4 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LTD (AU) | 2004-06-23 | — | — | EP | claimed |
| EP-1385379-A1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LIMITED (AU) | 2004-02-04 | — | — | EP | claimed |
| WO-2002078448-A1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LIMITED (AU) | 2002-10-10 | — | — | WO | claimed |
| EP-1385379-B1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LTD (AU) | 2008-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176424-A1 | Insecticide and method of controlling insects | DDT, CYP2B6, NR4A1 | PGD 4095/4885MEP1B 2655/4885MMP2 877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.