SCHEMBL4554492

SCHEMBL4554492

COP(=O)(O)CNC(Cc1ccccc1)C(=O)NO

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEP1B Q16820 2/20 0.50
HDAC8 Q9BY41 2/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC2 Q92769 1/20 0.49
ANPEP P15144 1/20 0.48
MMP8 P22894 2/20 0.46
LAP3 P28838 1/20 0.46
MMP2 P08253 2/20 0.45
MMP9 P14780 1/20 0.45
MMP1 P03956 1/20 0.44
MMP3 P08254 1/20 0.44
FPR2 P25090 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16415834 0.76 MME (0.49)
SCHEMBL4555303 0.76 MMP1 (0.41) ANPEPMMP8LAP3MMP2MMP9
SCHEMBL8697150 0.74 MME (0.47)
Ammonia Solution, Strong SCHEMBL2415758 0.73 MME (0.49) FPR2
SCHEMBL4436239 0.71 CTSS (0.68) HDAC8HDAC3HDAC4HDAC1HDAC2
SCHEMBL43350 0.71 MME (0.62) ANPEPLAP3
SCHEMBL43351 0.71 MME (0.62) ANPEPLAP3
SCHEMBL4430649 0.70 PGD (0.35) MEP1BHDAC8MMP8MMP2MMP9
SCHEMBL7417163 0.70 CTSL (0.68) MEP1BHDAC8HDAC3HDAC4HDAC1
SCHEMBL27520440 0.70 CTSL (0.68) MEP1BHDAC8HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4391747-B2 2009-12-24 JP claimed
US-7217831-B2 Insecticide and method of controlling insects NUFARM - AUSTRALIA LIMITED (AU) 2007-05-15 US claimed
JP-2004532837-A 2004-10-28 JP claimed
EP-1385379-A4 INSECTICIDE AND METHOD OF CONTROLLING INSECTS NUFARM AUSTRALIA LTD (AU) 2004-06-23 EP claimed
EP-1385379-A1 INSECTICIDE AND METHOD OF CONTROLLING INSECTS NUFARM AUSTRALIA LIMITED (AU) 2004-02-04 EP claimed
WO-2002078448-A1 INSECTICIDE AND METHOD OF CONTROLLING INSECTS NUFARM AUSTRALIA LIMITED (AU) 2002-10-10 WO claimed