Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.65 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.45 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236105 | 0.83 | CYP19A1 (0.58) | CYP19A1 | |
| SCHEMBL15841258 | 0.80 | CYP19A1 (0.50) | CYP19A1TUBBTP53NAMPTLMNA | |
| SCHEMBL2892895 | 0.79 | CYP19A1 (0.48) | CYP19A1TUBB | |
| SCHEMBL30386988 | 0.77 | ALDH1A1 (0.58) | CYP19A1LMNA | |
| SCHEMBL13747053 | 0.76 | CYP19A1 (0.44) | CYP19A1TUBBTP53NAMPTLMNA | |
| SCHEMBL10093334 | 0.76 | CYP19A1 (0.54) | CYP19A1 | |
| SCHEMBL12919524 | 0.76 | RAB9A (0.47) | CYP19A1LMNA | |
| SCHEMBL2896014 | 0.74 | CYP19A1 (0.56) | CYP19A1TBXA2R | |
| SCHEMBL2896768 | 0.74 | HSD17B1 (0.47) | LMNA | |
| SCHEMBL2010148 | 0.74 | ALDH1A1 (0.52) | TBXA2RTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137141-A1 | BIPHENYL-4-YL-SULFONIC ACID ARYLAMIDES AND THEIR USE AS THERAPEUTIC AGENTS | The University Court of The University of Aberdeen (GB) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008114022-A1 | BIPHENYL-4-YL-SULFONIC ACID ARYLAMIDES AND THEIR USE AS THERAPEUTIC AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2008-09-25 | — | — | WO | disclosed |