Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3981454 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2724085 | 0.84 | SMN1; SMN2 (0.66) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL8880593 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL15498865 | 0.83 | KDM4E (0.49) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2730319 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL3055067 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL21561297 | 0.80 | NAAA (0.72) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL3981746 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4433418 | 0.80 | MEN1 (0.61) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL11972337 | 0.80 | RAB9A (0.57) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012485-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2013-01-10 | — | — | US | disclosed |
| EP-2124913-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | Novartis AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077597-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012485-A1 | ORGANIC COMPOUNDS | DPP4, DPP3, DPP7 | SMN1; SMN2 2612/4885KDM4E 647/4885RAB9A 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.