Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730319 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4ECYP1A2RAB9AMEN1 | |
| SCHEMBL11972337 | 0.85 | RAB9A (0.57) | SMN1; SMN2KDM4ECYP1A2RAB9AMEN1 | |
| SCHEMBL3981454 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4ECYP1A2RAB9AMEN1 | |
| SCHEMBL3055067 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4ECYP1A2RAB9AMEN1 | |
| SCHEMBL2724085 | 0.84 | SMN1; SMN2 (0.66) | SMN1; SMN2KDM4ECYP1A2RAB9AMEN1 | |
| SCHEMBL4430875 | 0.83 | SMN1; SMN2 (0.69) | SMN1; SMN2KDM4ECYP1A2RAB9AMEN1 | |
| SCHEMBL8878334 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4ECYP1A2RAB9AMEN1 | |
| SCHEMBL9848202 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4ECYP1A2RAB9AMEN1 | |
| SCHEMBL15774486 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4ECYP1A2RAB9AMEN1 | |
| SCHEMBL3981746 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4ECYP1A2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602160-A | MUSCLE RELAXANT | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1997-02-11 | — | — | US | disclosed |
| US-5498619-A | MUSCLE RELAXANTS, POLLAKIUREA CURING AGENTS AND MUSCLE SPASMS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0414391-B1 | Aminoketone derivatives and use thereof | MITSUI TOATSU CHEMICALS (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5338857-A | Muscle relaxant | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0414391-A2 | Aminoketone derivatives and use thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-02-27 | — | — | EP | disclosed |