Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608932 | 0.86 | HTR2B (0.36) | IDO1CYP3A4 | |
| SCHEMBL4429993 | 0.81 | S1PR4 (0.38) | ABL1KDM4E | |
| SCHEMBL27978155 | 0.79 | MAP4K4 (0.41) | MAP4K4IDO1CYP3A4ABL1AGPAT2 | |
| SCHEMBL4429899 | 0.79 | AGPAT2 (0.33) | AGPAT2S100A4 | |
| SCHEMBL512419 | 0.77 | ALOX5 (0.42) | CYP3A4JAK2 | |
| SCHEMBL4430076 | 0.76 | ALDH1A1 (0.35) | L3MBTL1KDM4E | |
| SCHEMBL374592 | 0.76 | MCL1 (0.45) | CYP3A4 | |
| SCHEMBL16574093 | 0.75 | MAP4K4 (0.51) | MAP4K4IDO1CYP3A4ABL1AGPAT2 | |
| SCHEMBL4437593 | 0.75 | NOTUM (0.43) | ABL1NOTUM | |
| SCHEMBL13176931 | 0.74 | MAP4K4 (0.50) | MAP4K4IDO1CYP3A4ABL1AGPAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |