SCHEMBL4431950

SCHEMBL4431950

FC(F)(F)Cc1c[c]c(Br)cc1-c1cccc(Br)c1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
KDM4E B2RXH2 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
RXFP1 Q9HBX9 1/20 0.32
MAPT P10636 3/20 0.30
HPGD P15428 2/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HSD17B10 Q99714 1/20 0.30
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085471 0.75 MEN1 (0.37) MEN1KMT2AKDM4ESMN1; SMN2RXFP1
SCHEMBL4431948 0.74 MEN1 (0.33) MEN1KMT2AKDM4ESMN1; SMN2RXFP1
SCHEMBL5085694 0.69 PTPN5 (0.34)
SCHEMBL4427523 0.68 PTGES (0.35) ALDH1A1
SCHEMBL2222181 0.68 MAOB (0.35) MEN1KMT2AKDM4ESMN1; SMN2RXFP1
SCHEMBL15063620 0.64 RAB9A (0.41) MEN1KMT2AKDM4ESMN1; SMN2MAPT
SCHEMBL5086336 0.64 ADRA2C (0.44)
SCHEMBL15476972 0.63 TAAR1 (0.50) SMN1; SMN2
SCHEMBL30228696 0.63 TAAR1 (0.50) SMN1; SMN2
SCHEMBL5085470 0.63 RAB9A (0.37) MEN1KMT2AKDM4ESMN1; SMN2RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121660-A2 FUNGICIDAL AMIDES E. I. Du Pont de Nemours and Company (US) 2009-11-25 EP disclosed
WO-2008091580-A2 FUNGICIDAL AMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed
EP-1948649-A2 FUNGICIDAL CARBOXAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-30 EP disclosed
WO-2007014290-A2 FUNGICIDAL CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-01 WO disclosed