Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645335 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2THRBMAPTMEN1RECQL | |
| SCHEMBL3884110 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2THRBMAPTMEN1RECQL | |
| SCHEMBL4440012 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2THRBMAPTMEN1RECQL | |
| SCHEMBL1646251 | 0.82 | L3MBTL1 (0.50) | SMN1; SMN2THRBMAPTMEN1RECQL | |
| SCHEMBL1644577 | 0.79 | LMNA (0.46) | SMN1; SMN2THRBMAPTMEN1KMT2A | |
| SCHEMBL1646576 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2THRBMAPTMEN1RECQL | |
| SCHEMBL1646671 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2THRBMAPTMEN1RECQL | |
| SCHEMBL29697806 | 0.78 | MMP1 (0.41) | SMN1; SMN2THRBKDM4EALDH1A1BCAT2 | |
| SCHEMBL1645505 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2THRBMAPTMEN1RECQL | |
| SCHEMBL1645503 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2THRBMAPTMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097413-A1 | 2-[(2-SUBSTITUTED)-IND0LIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008062182-A1 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2008-05-29 | — | — | WO | disclosed |