Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12056798 | 0.89 | ACHE (0.39) | L3MBTL1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL8939008 | 0.87 | L3MBTL1 (0.38) | L3MBTL1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL32685566 | 0.85 | ACHE (0.36) | L3MBTL1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL15315292 | 0.85 | ACHE (0.36) | L3MBTL1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL11703843 | 0.85 | L3MBTL1 (0.39) | L3MBTL1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL3922521 | 0.80 | SCN4A (0.42) | L3MBTL1MAPTALDH1A1TSHRMAPK1 | |
| SCHEMBL3418221 | 0.79 | CYP1A2 (0.38) | L3MBTL1MAPTTSHRLMNAHTR1A | |
| SCHEMBL8927376 | 0.77 | ACHE (0.39) | L3MBTL1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL3871597 | 0.76 | HPGD (0.40) | L3MBTL1MAPTHPGDTSHRMAPK1 | |
| SCHEMBL18121978 | 0.76 | KDM4E (0.39) | L3MBTL1MAPTALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114568-B1 | PHOSPHONITE-CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES | EASTMAN CHEM CO (US) | 2013-05-08 | — | — | EP | disclosed |
| EP-2114568-A1 | PHOSPHONITE-CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES | Eastman Chemical Company (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008088495-A1 | PHOSPHONITE-CONTAINING CATALYSTS FOR HYDROFORMYLATION PROCESSES | EASTMAN CHEMICAL COMPANY (US) | 2008-07-24 | — | — | WO | disclosed |