SCHEMBL3871597

SCHEMBL3871597

Cc1ccc(OP(Oc2ccccc2)Oc2ccccc2)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.40
L3MBTL1 Q9Y468 4/20 0.40
TSHR P16473 2/20 0.40
MAPK1 P28482 2/20 0.40
MAPT P10636 2/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
HCRTR1 O43613 1/20 0.36
CYP2A6 P11509 1/20 0.36
HTR1A P08908 1/20 0.36
HTR3A P46098 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12810348 0.88 L3MBTL1 (0.47) HPGDL3MBTL1TSHRMAPK1MAPT
SCHEMBL470419 0.87 ACHE (0.44) HPGDL3MBTL1TSHRMAPK1MAPT
SCHEMBL12810471 0.85 L3MBTL1 (0.42) HPGDL3MBTL1TSHRMAPK1MAPT
SCHEMBL27838850 0.84 DRD2 (0.43) HPGDTSHRMAPTNPC1RAB9A
SCHEMBL28571280 0.81 DRD2 (0.41) HPGDTSHRNPC1RAB9ASMN1; SMN2
SCHEMBL27704653 0.81 DRD2 (0.41) HPGDTSHRNPC1RAB9ASMN1; SMN2
SCHEMBL12810270 0.81 DRD2 (0.41) HPGDTSHRNPC1RAB9ASMN1; SMN2
SCHEMBL446426 0.80 HTT (0.48) HPGDTSHRMAPTSMN1; SMN2LMNA
SCHEMBL444404 0.80 HTT (0.48) HPGDTSHRMAPTSMN1; SMN2LMNA
SCHEMBL27704654 0.80 HTT (0.48) HPGDTSHRMAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4198492-A BLEND WITH A STYRENE-TYPE POLYMER, A DIBENZO(C,E)-1,2-OXAPHOSPHORIN AND A PHOSPHITE, A MELAMINE OR A BENZOGUANAMINE ASAHI-DOW LIMITED (JP) 1980-04-15 US claimed
US-7517838-B2 Lubricating oil for bearing NEW JAPAN CHEMICAL CO., LTD. (JP) 2009-04-14 US disclosed
US-7351766-B2 polycrbonate compatible homo/copolymer of akyl(meth)acrylate, copolymer of an aromatic alkenyl -vinyl cyanide monomer, copolymer of alkyl(meth)acrylate- vinyl cyanide or aromatic alkenyl monomer graft polymerized with polycarbonate incompatible polyalkyl(meth)acrylate or polyorganosiloxane; fluidity MITSUBISHI RAYON CO., LTD. (JP) 2008-04-01 US disclosed
US-20060019840-A1 Lubricating oil for bearing NEW JAPAN CHEMICAL CO., LTD. (JP) 2006-01-26 US disclosed
US-20050159533-A1 polycrbonate compatible homo/copolymer of akyl(meth)acrylate, copolymer of an aromatic alkenyl -vinyl cyanide monomer, copolymer of alkyl(meth)acrylate- vinyl cyanide or aromatic alkenyl monomer graft polymerized with polycarbonate incompatible polyalkyl(meth)acrylate or polyorganosiloxane; fluidity MITSUBISHI RAYON CO., LTD. (JP) 2005-07-21 US disclosed
US-6384114-B1 THERMOPLASTIC RESIN COMPOSITION CONSISTING ESSENTIALLY OF RESIN MIXTURE OF POLYCARBONATE RESIN, STYRENIC RESIN, PHOSPHATE ESTER MONOMER, OLIGOMER AND/OR POLYMER AND FLUORO-OLEFINIC RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-05-07 US disclosed
EP-0580308-B1 Working fluid composition for refrigeration machine KAO CORP (JP) 2000-11-15 EP disclosed
US-6096692-A CYLIC KETALS AND ACDTALS HAVING HEAT AND OXIDATION RESISTANCE, ARE FREE FROM CARBOXYLIC ACIDS FORMING DUE TO HYDROLYSIS, LOW IN HYGROSCOPICITY, INEXPENSIVE, GOOD INSULATION AND COMPATIBLE WITH HYDROFLUOROCARBONS; WORKING FLUID REFRIGERANTS KAO CORPORATION (JP) 2000-08-01 US disclosed
EP-0779289-A1 SYNTHETIC LUBRICATING OIL Kao Corporation (JP) 1997-06-18 EP disclosed
EP-0475751-B1 Working fluid composition for refrigerating machine KAO CORP (JP) 1995-12-06 EP disclosed
US-5395544-A Ester-containing working fluid composition for refrigerating machine KAO CORPORATION (JP) 1995-03-07 US disclosed
US-5364899-A Polycarbonate, zinc carboxylate, glass fibers, polytetrafluoroethylene, polydimethysiloxane, triphenyl phosphate DENKI KAGAKU KOGUO KABUSHIKI KAISHA (JP) 1994-11-15 US disclosed
EP-0580308-A1 Working fluid composition for refrigeration machine KAO CORPORATION (JP) 1994-01-26 EP disclosed
US-5202044-A Mixture of fluorohydrocarbon, epoxycyclo(pentane or hexane), and ester KAO CORPORATION (JP) 1993-04-13 US disclosed
EP-0501440-A1 Composition for refrigerator working fluid use KAO CORPORATION (JP) 1992-09-02 EP disclosed
EP-0475751-A1 Working fluid composition for refrigerating machine Kao Corporation (JP) 1992-03-18 EP disclosed
US-4228064-A CYCLIC PHOSPHORUS-CONTAINING COMPOUNDS ASAKI-DOW LIMITED (JP) 1980-10-14 US disclosed
US-4198492-A BLEND WITH A STYRENE-TYPE POLYMER, A DIBENZO(C,E)-1,2-OXAPHOSPHORIN AND A PHOSPHITE, A MELAMINE OR A BENZOGUANAMINE ASAHI-DOW LIMITED (JP) 1980-04-15 US disclosed