Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5141361 | 0.84 | TSHR (0.57) | TSHRGFERCYP3A4HSD17B10KIF11 | |
| SCHEMBL25973862 | 0.80 | TSHR (0.59) | CYP2A6TSHRGFERMAPK1HSD17B10 | |
| SCHEMBL28788627 | 0.79 | CYP2A6 (0.52) | CYP2A6MAOBDHODHUSP7HSD17B10 | |
| SCHEMBL22270544 | 0.78 | DPP4 (0.44) | CYP1A2CYP3A4CYP2D6CYP2C9MAPK1 | |
| SCHEMBL6674385 | 0.77 | CA12 (0.48) | TSHRGFERCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27636093 | 0.76 | CSNK2A1 (0.49) | CYP2A6DHODHTSHRHSD17B10HSD11B1 | |
| SCHEMBL27717693 | 0.76 | CYP2A6 (0.48) | CYP2A6MAOBDHODHUSP7TAAR1 | |
| SCHEMBL1045000 | 0.76 | CYP2A6 (0.65) | CYP2A6MAOBTSHRUSP7TDP1 | |
| SCHEMBL23546571 | 0.75 | TSHR (0.46) | TSHRGFERCYP3A4HSD17B10KIF11 | |
| SCHEMBL6490058 | 0.75 | ALDH1A1 (0.58) | TSHRGFERMAPK1KIF11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009057133-A2 | A PROCESS FOR THE SYNTHESIS OF 2-[2-[4-[(4-CHLOROPHENYL)PHENYL METHYL]-1-PIPERAZINYL] ETHOXY ACETIC ACID | GLENMARK GENERICS LIMITED (IN) | 2009-05-07 | — | — | WO | disclosed |
| CN-1708476-A | Novel amide compounds having MCH-antagonistic action and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-12-14 | — | — | CN | disclosed |