Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27450693 | 0.90 | CYP2A6 (0.59) | CYP2A6MAOBTNKS2KMT2AMEN1 | |
| SCHEMBL1047922 | 0.82 | CNR2 (0.50) | CYP2A6 | |
| SCHEMBL8036362 | 0.82 | LMNA (0.50) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL6436152 | 0.80 | CYP2A6 (0.90) | CYP2A6MAOBHSD11B1ALDH1A1HPGD | |
| SCHEMBL29453518 | 0.80 | CYP2A6 (0.71) | CYP2A6MAOBALDH1A1KDM4EHPGD | |
| SCHEMBL671819 | 0.80 | CYP2A6 (0.71) | CYP2A6MAOBALDH1A1KDM4EHPGD | |
| SCHEMBL11260432 | 0.80 | HSD11B1 (0.47) | CYP2A6HSD11B1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12999509 | 0.80 | RAB9A (0.46) | CYP2A6MAOBKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL12431877 | 0.80 | BACE1 (0.53) | CYP2A6HSD11B1TNKS2KMT2AMEN1 | |
| SCHEMBL23628571 | 0.79 | CYP2A6 (1.00) | CYP2A6MAOBHSD11B1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117116-A | A kind of noval chemical compound 9 (4 ' methyl biphenyl) 3 nitrocarbazoles and synthetic method thereof | 别福升 | 2016-11-16 | — | — | CN | claimed |
| CN-101328191-B | Nitrogen-containing ligand transient metal complex compound , synthetic method and use thereof | SHANGHAI INST ORGANIC CHEM | 2013-06-05 | — | — | CN | claimed |
| CN-118852231-A | Heterogeneous palladium-catalyzed C (sp2) -H bond silylation reaction | 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) | 2024-10-29 | — | — | CN | disclosed |
| CN-114292261-B | Compound and application thereof | 北京燕化集联光电技术有限公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2023002447-A1 | ORGANIC LIGHT-EMITTING DEVICE | 주식회사 엘지화학 | 2023-01-26 | — | — | WO | disclosed |
| CN-114292261-A | Compound and application thereof | 北京燕化集联光电技术有限公司 | 2022-04-08 | — | — | CN | disclosed |
| EP-3242875-B1 | 4,5-DIHYDROIMIDAZOLE DERIVATIVES AND THEIR USE AS HISTONE DEMETHYLASE (KDM2B) INHIBITORS | GENENTECH INC (US) | 2022-02-23 | — | — | EP | disclosed |
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2020-12-17 | — | — | US | disclosed |
| CN-106117116-B | A kind of noval chemical compound 9- (4 '-methyl biphenyl) -3- nitrocarbazoles and its synthetic method | 枣庄学院 | 2018-08-31 | — | — | CN | disclosed |
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2017-07-06 | — | — | US | disclosed |
| EP-3153501-A1 | GLUCAGON ANTAGONISTS | Metabasis Therapeutics, Inc. (US) | 2017-04-12 | — | — | EP | disclosed |
| US-6080870-A | Biaryl substituted imidazole compounds useful as farnesyl-protein transferase inhibitors | MERCK & CO., INC. (US) | 2000-06-27 | — | — | US | disclosed |
| EP-1000619-A2 | Method for treating glaucoma | Pfizer Products Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0946501-A1 | PREVENTION OF LOSS AND RESTORATION OF BONE MASS BY CERTAIN PROSTAGLANDIN AGONISTS | PFIZER INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| EP-0934236-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED AROMATIC COMPOUNDS | Zeneca Limited (GB) | 1999-08-11 | — | — | EP | disclosed |
| CN-1215396-A | Diarylmethylidene furan derivatives, preparation method and therapeutic use thereof | UNION PHARMA SCIENT APPL (FR) | 1999-04-28 | — | — | CN | disclosed |
| EP-0891333-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998028264-A1 | PREVENTION OF LOSS AND RESTORATION OF BONE MASS BY CERTAIN PROSTAGLANDIN AGONISTS | PFIZER INC. (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998016486-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1998-04-23 | — | — | WO | disclosed |
| WO-1997036875-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190669-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, FAAH, FAAH2 | CYP2A6 48/4885MAOB 1578/4885HSD11B1 3098/4885 |
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, LOX | CYP2A6 1089/4885MAOB 101/4885HSD11B1 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.